The effect of Na + ‐Ca 2+ exchange on the recovery from Ca 2+ dependent inactivation of L‐type Ca 2+ channel in cardiomyocytes in pulmonary vein
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Effects of Phospholipase C on the Na + - Ca 2 + Exchange and Ca 2 + Permeability of Cardiac
We have examined the effects of phospholipase C pretreatment on Ca2+ transport in highly purified canine cardiac sarcolemmal vesicles. Na+-Ca2+ exchange, measured as Nai+-dependent Caz+ uptake, is stimulated when 10-70% of the membrane phospholipid has been hydrolyzed. Although the phospholipase C treatment also increases sarcolemmal passive Ca2+ flux, the membrane maintains a sufficient permea...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2010
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.24.1_supplement.595.1